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butabarbital will minimize the extent or effect of sulfamethoxazole by affecting hepatic enzyme CYP2C9/ten metabolism. Slight/Significance Unknown.butabarbital will lower the extent or impact of midazolam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe.butabarbital will lessen the level or impact of hydrocortisone by i

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